منابع مشابه
Awakening from Sleep and Hypoglycemia in Type 1 Diabetes Mellitus
The Diabetes Control and Complications Trial in type 1 diabetes (T1DM) unequivocally showed the benefi ts of good glycemic control in preventing the complications of diabetes. Despite the treatment advances of the past decade, today iatrogenic hypoglycemia remains the major impediment to the appropriate control of blood glucose [1]. While imperfect insulin replacement places the patient at incr...
متن کاملInsight into hypoglycemia in pediatric type 1 diabetes mellitus
Hypoglycemia is a common complication of insulin treatment in type 1 diabetes mellitus and can occur in any patient with diabetes when glucose consumption exceeds supply. Many studies have been done to elucidate those factors that predict severe hypoglycemia: younger age, longer duration of diabetes, lower HgbA1c, higher insulin dose, lower Body Mass Index, male gender, Caucasian race, underins...
متن کاملSeasonal Variations of Severe Hypoglycemia in Patients With Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, and Non-diabetes Mellitus
Blood glucose control in patients with diabetes mellitus (DM) is reportedly influenced by the seasons, with hemoglobin A1c (HbA1c) levels decreasing in the summer or warm season and increasing in the winter or cold season. In addition, several studies have shown that sepsis is also associated with the seasons. Although both blood glucose control and sepsis can strongly affect the occurrence of ...
متن کاملHypoglycemia in Type 1 Diabetes
In subjects with type 1 diabetes, autoimmune destruction of pancreatic -cells leads eventually to an absolute requirement for insulin replacement therapy. Insulin delivered exogenously is not subject to normal physiological feedback regulation, so it may induce hypoglycemia even in the presence of an intact counterregulatory response. The average individual with type 1 diabetes experiences abou...
متن کاملType 1 Diabetes and Hypoglycemia
Type 1 Diabetes and the -Cell Matthias von Herrath (La Jolla, CA) received the American Diabetes Association (ADA) 2008 Outstanding Scientific Achievement Award for his research on approaches to -cell–specific immune interventions for type 1 diabetes. He began with a discussion of the evidence of a role of viral infections in the development of type 1 diabetes. In experimental models, viral inf...
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ژورنال
عنوان ژورنال: Endocrinology and Metabolism Clinics of North America
سال: 2010
ISSN: 0889-8529
DOI: 10.1016/j.ecl.2010.05.003